Drsmooth provides tools for assessing the shape of a dose-response curve by testing linearity and non-linearity at user-defined cut-offs. It also provides two methods of estimating a threshold dose, or the dose at which the dose-response function transitions to significantly increasing: bi-linear (based on pkg:segmented) and smoothed with splines (based on pkg:mgcv).
| Version: | 1.0 |
| Depends: | R (≥ 3.0.1) |
| Imports: | car, clinfun, mgcv, multcomp, pgirmess, DTK, segmented, mvtnorm |
| Suggests: | testthat |
| Published: | 2013-12-05 |
| Author: | Greg Hixon [aut, cph], Anne Bichteler [aut, cre], Chad Thompson [ctb], Liz Abraham [ctb] |
| Maintainer: | Anne Bichteler <abichteler at toxstrategies.com> |
| License: | GPL (≥ 3) |
| NeedsCompilation: | no |
| CRAN checks: | drsmooth results |
| Reference manual: | drsmooth.pdf |
| Package source: | drsmooth_1.0.tar.gz |
| Windows binaries: | r-devel: drsmooth_1.0.zip, r-release: drsmooth_1.0.zip, r-oldrel: drsmooth_1.0.zip |
| OS X Snow Leopard binaries: | r-release: drsmooth_1.0.tgz, r-oldrel: drsmooth_1.0.tgz |
| OS X Mavericks binaries: | r-release: not available |