drsmooth: Dose-Response Modeling with Smoothing Splines

Drsmooth provides tools for assessing the shape of a dose-response curve by testing linearity and non-linearity at user-defined cut-offs. It also provides two methods of estimating a threshold dose, or the dose at which the dose-response function transitions to significantly increasing: bi-linear (based on pkg:segmented) and smoothed with splines (based on pkg:mgcv).

Version: 1.0
Depends: R (≥ 3.0.1)
Imports: car, clinfun, mgcv, multcomp, pgirmess, DTK, segmented, mvtnorm
Suggests: testthat
Published: 2013-12-05
Author: Greg Hixon [aut, cph], Anne Bichteler [aut, cre], Chad Thompson [ctb], Liz Abraham [ctb]
Maintainer: Anne Bichteler <abichteler at toxstrategies.com>
License: GPL (≥ 3)
NeedsCompilation: no
CRAN checks: drsmooth results


Reference manual: drsmooth.pdf
Package source: drsmooth_1.0.tar.gz
Windows binaries: r-devel: drsmooth_1.0.zip, r-release: drsmooth_1.0.zip, r-oldrel: drsmooth_1.0.zip
OS X Snow Leopard binaries: r-release: drsmooth_1.0.tgz, r-oldrel: drsmooth_1.0.tgz
OS X Mavericks binaries: r-release: not available