BiSEp: Toolkit to identify synthetic lethality and cell line resistance relationships based on bimodality in gene expression data

Enables the user to infer potential synthetic lethal relationships by analysing relationships between bimodally distributed gene pairs in big gene expression datasets. Enables the user to look for enrichment of resistance to a compound in individual bimodal genes.

Version: 1.0
Depends: R (≥ 3.0.1), mclust (≥ 4.2.0), GOSemSim (≥ 1.20.0), GO.db (≥ 2.10.1), org.Hs.eg.db (≥ 2.10.1)
Published: 2014-02-25
Author: Mark Wappett
Maintainer: Mark Wappett <mark.wappett at astrazeneca.com>
License: Artistic-2.0
NeedsCompilation: no
CRAN checks: BiSEp results

Downloads:

Reference manual: BiSEp.pdf
Package source: BiSEp_1.0.tar.gz
Windows binaries: r-devel: BiSEp_1.0.zip, r-release: BiSEp_1.0.zip, r-oldrel: BiSEp_1.0.zip
OS X Snow Leopard binaries: r-release: BiSEp_1.0.tgz, r-oldrel: not available
OS X Mavericks binaries: r-release: BiSEp_1.0.tgz