pocrm: Dose-finding in drug combination Phase I trials using the partial order continual reassessment method (PO-CRM)

This package provides functions to implement and simulate the partial order continual reassessment method (PO-CRM) for use in Phase I trials of combinations of agents. It also provides a function for generating a set of initial guesses (skeleton) for the toxicity probabilities at each combination that correspond to the set of possible orderings of the toxicity probabilities specified by the user.

Version: 0.8
Depends: dfcrm, nnet
Published: 2014-07-24
Author: Nolan A. Wages
Maintainer: "Varhegyi, Nikole (nev4g)" <nev4g at eservices.virginia.edu>
License: GPL-2
NeedsCompilation: no
CRAN checks: pocrm results


Reference manual: pocrm.pdf
Package source: pocrm_0.8.tar.gz
Windows binaries: r-devel: pocrm_0.8.zip, r-release: pocrm_0.8.zip, r-oldrel: pocrm_0.8.zip
OS X Snow Leopard binaries: r-release: pocrm_0.8.tgz, r-oldrel: pocrm_0.8.tgz
OS X Mavericks binaries: r-release: pocrm_0.8.tgz
Old sources: pocrm archive