The DoseFinding package provides functions for the design and analysis of dose-finding experiments (with focus on pharmaceutical Phase II clinical trials). It provides functions for: multiple contrast tests, fitting non-linear dose-response models (using Bayesian and non-Bayesian estimation), calculating optimal designs and an implementation of the MCPMod methodology.
| Version: | 0.9-12 |
| Depends: | lattice, mvtnorm, R (≥ 2.15.0) |
| Suggests: | numDeriv, Rsolnp, quadprog, parallel, multcomp |
| Published: | 2014-09-28 |
| Author: | Bjoern Bornkamp, Jose Pinheiro, Frank Bretz |
| Maintainer: | Bjoern Bornkamp <bbnkmp at gmail.com> |
| License: | GPL-3 |
| NeedsCompilation: | yes |
| Materials: | ChangeLog |
| In views: | ClinicalTrials, ExperimentalDesign |
| CRAN checks: | DoseFinding results |
| Reference manual: | DoseFinding.pdf |
| Package source: | DoseFinding_0.9-12.tar.gz |
| Windows binaries: | r-devel: DoseFinding_0.9-12.zip, r-release: DoseFinding_0.9-12.zip, r-oldrel: DoseFinding_0.9-12.zip |
| OS X Snow Leopard binaries: | r-release: DoseFinding_0.9-12.tgz, r-oldrel: DoseFinding_0.9-12.tgz |
| OS X Mavericks binaries: | r-release: DoseFinding_0.9-12.tgz |
| Old sources: | DoseFinding archive |
| Reverse imports: | uniReg |