SmoothHazard: Fitting illness-death model for interval-censored data

SmoothHazard is a package for fitting illness-death (and survival) model with possibly interval-censored data for transition toward transient state. Left-truncated and right-censored data are also allowed. Proportional intensities regression models allow for covariates on each of the 3 transitions. We use either a parametric approach with Weibull baseline intensities or a semi-parametric approach with M-splines approximation of baseline intensities in order to obtain smooth estimates. Estimation of parameters is conducted by likelihood maximization in the parametric approach or penalized likelihood maximization in the semi-parametric approach.

Version: 1.2.3
Depends: R (≥ 1.9.1)
Imports: lava, mvtnorm, prodlim
Published: 2014-09-19
Author: Celia Touraine, Pierre Joly, Thomas A. Gerds
Maintainer: Thomas Alexander Gerds <tag at>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: yes
In views: Survival
CRAN checks: SmoothHazard results


Reference manual: SmoothHazard.pdf
Package source: SmoothHazard_1.2.3.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
OS X Snow Leopard binaries: r-release: SmoothHazard_1.2.3.tgz, r-oldrel: SmoothHazard_1.2.3.tgz
OS X Mavericks binaries: r-release: SmoothHazard_1.2.3.tgz
Old sources: SmoothHazard archive