SimReg: Similarity Regression Functions

Functions for performing Bayesian ‘similarity regression’, adapted to model the association between an HPO-encoded patient phenotype and binary genotype. A ‘no association’ model is compared with one in which the log odds of having a rare genotype is linked to the semantic similarity between patient phenotype and a latent characteristic phenotype. The method estimates the probability of an association together with an HPO-coded phenotype characteristic of the disease.

Version: 1.2
Depends: R (≥ 3.0.0), hpoPlot
Imports: Rcpp (≥ 0.11.1), dplyr, parallel, ggplot2, plotrix, gridExtra, reshape2
LinkingTo: Rcpp
Published: 2015-09-15
Author: Daniel Greene
Maintainer: Daniel Greene <dg333 at>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: yes
CRAN checks: SimReg results


Reference manual: SimReg.pdf
Package source: SimReg_1.2.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
OS X Snow Leopard binaries: r-release: not available, r-oldrel: not available
OS X Mavericks binaries: r-release: SimReg_1.2.tgz
Old sources: SimReg archive