Generates time-to-event family data associated with mutated genes arising from various family study designs such as population-based, clinic- based, or multi-stage designs and provides functions to fit family data accounting for the study design and estimate age-dependent penetrance functions. It also provides carrier probabilities for those with missing genotypes and penetrance estimations are based on an Expectation-Maximization algorithm when genotypes are missing.
| Version: |
1.0 |
| Depends: |
R (≥ 3.0.0), base, MASS, truncnorm, survival, kinship2 |
| Published: |
2016-02-09 |
| Author: |
Yun-Hee Choi, Karen Kopciuk, Wenqing He, Laurent Briollais |
| Maintainer: |
Yun-Hee Choi <yun-hee.choi at schulich.uwo.ca> |
| License: |
GPL-2 | GPL-3 [expanded from: GPL (≥ 2.0)] |
| NeedsCompilation: |
no |
| CRAN checks: |
FamEvent results |