edmr: Empirical Differentially Methylated Regions Calculation

Optimized DMR analysis based on bimodal normal distribution model and cost function for regional methylation analysis optimization. It captures the regional methylation modification by taking the spatial distribution of CpGs into account for the enrichment DNA methylation sequencing data so as to optimize the definition of the empirical regions. Combined with the dependent adjustment for regional p-value combination and DMR annotation.

Depends: R (≥ 3.2.1)
Imports: GenomicRanges, IRanges, data.table, mixtools, S4Vectors
Published: 2015-07-09
Author: Sheng Li [aut, cre, cph], Francine Garrett-Bakelman [ctb], Altuna Akalin [ctb], Paul Zumbo [ctb], Ari Melnick [ctb], Chris Mason [ctb, ths]
Maintainer: Sheng Li <shelly1436 at gmail.com>
License: Artistic-2.0
URL: https://github.com/ShengLi/edmr
NeedsCompilation: no
Citation: edmr citation info
Materials: README
CRAN checks: edmr results


Reference manual: edmr.pdf
Package source: edmr_0.6.3.1.tar.gz
Windows binaries: r-devel: edmr_0.6.3.1.zip, r-release: edmr_0.6.3.1.zip, r-oldrel: not available
OS X Snow Leopard binaries: r-release: not available, r-oldrel: not available
OS X Mavericks binaries: r-release: edmr_0.6.3.1.tgz
Old sources: edmr archive