Purpose of this package is it to plan, monitor and evaluate oncological phase II studies. In general this kind of studies are single-arm trials with planned interim analysis and binary endpoint. To meet the resulting requirements, the package provides functions to calculate and evaluate 'Simon's two-stage designs' and 'so-called' 'subset designs'. If you are unfamiliar with this package a good starting point is to take a closer look at the functions getSolutions() and getSolutionsSub1().The web-based tool (https://imbi.shinyapps.io/phaseII-app/) extends the functionality of our R package by means of a proper dealing with over- and underrunning. The R function binom.test of the 'stats' R package and the package 'binom' might be helpful to assess the performance of the corresponding one-stage design as a reference.
| Version: | 0.1.6 |
| Depends: | methods, stats, Rcpp (≥ 0.9.11), R (≥ 3.1.0) |
| LinkingTo: | Rcpp |
| Published: | 2016-05-23 |
| Author: | Marius Wirths |
| Maintainer: | Marius Wirths <wirths at imbi.uni-heidelberg.de> |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | yes |
| CRAN checks: | OneArmPhaseTwoStudy results |
| Reference manual: | OneArmPhaseTwoStudy.pdf |
| Package source: | OneArmPhaseTwoStudy_0.1.6.tar.gz |
| Windows binaries: | r-devel: OneArmPhaseTwoStudy_0.1.6.zip, r-release: OneArmPhaseTwoStudy_0.1.6.zip, r-oldrel: OneArmPhaseTwoStudy_0.1.6.zip |
| OS X Mavericks binaries: | r-release: OneArmPhaseTwoStudy_0.1.6.tgz, r-oldrel: OneArmPhaseTwoStudy_0.1.6.tgz |
| Old sources: | OneArmPhaseTwoStudy archive |
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