Conduct multi-locus GWAS and multi-locus QTL mapping under the framework of random-SNP-effect mixed linear model (mrMLM). First, each position (or marker) on the genome is scanned by mrMLM algorithm. Bonferroni correction is replaced by a less stringent selection criterion for significant test. Then, all the markers (or QTL) that are potentially associated with the trait are included in a multi-locus model, their effects are estimated by empirical Bayes and true QTN or QTL are identified by likelihood ratio test.
| Version: | 2.0 |
| Depends: | gWidgets, gWidgetsRGtk2, RGtk2Extras, MASS |
| Imports: | RGtk2, methods, openxlsx, stringr, ggplot2, qqman |
| Published: | 2016-12-20 |
| Author: | Wenlong Ren,Yuanli Ni,Shibo Wang,Yangjun Wen,Bo Huang and Yuanming Zhang |
| Maintainer: | Yuanming Zhang <soyzhang at mail.hzau.edu.cn> |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | no |
| CRAN checks: | mrMLM results |
| Reference manual: | mrMLM.pdf |
| Package source: | mrMLM_2.0.tar.gz |
| Windows binaries: | r-devel: mrMLM_2.0.zip, r-release: mrMLM_2.0.zip, r-oldrel: mrMLM_2.0.zip |
| OS X Mavericks binaries: | r-release: mrMLM_2.0.tgz, r-oldrel: mrMLM_2.0.tgz |
| Old sources: | mrMLM archive |
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