The output of an affinity-purification mass spectrometry experiment is typically a list of proteins that were observed in the experiment, identified by UniProt identifiers (http://www.uniprot.org/). This package takes as input a list of UniProt identifiers, and the associated Mascot scores from the experiment (which indicate the likelihood that the protein has been correctly identified), clusters them by gene ontology category (http://geneontology.org/), then draws diagrams showing the results in hierarchical clusters by category, with lines for individual proteins representing the associated Mascot score. The results are in general not publication-ready, but will rather require editing via a graphics editor that can interpret SVG (scalable vector graphics) format. As an alternative representation, the package will also generate tag clouds based on the Mascot scores.
Version: | 1.4.5 |
Depends: | R (≥ 3.1.0) |
Imports: | AnnotationDbi, gplots, XLConnect, wordcloud, RColorBrewer |
Suggests: | GO.db, org.Hs.eg.db, org.Mm.eg.db |
Published: | 2015-01-27 |
Author: | Gord Brown, Hisham Mohammed |
Maintainer: | Gord Brown <gdbzork at gmail.com> |
License: | Artistic-2.0 |
NeedsCompilation: | no |
Citation: | msarc citation info |
CRAN checks: | msarc results |
Reference manual: | msarc.pdf |
Vignettes: |
Using msarc |
Package source: | msarc_1.4.5.tar.gz |
Windows binaries: | r-devel: msarc_1.4.5.zip, r-release: msarc_1.4.5.zip, r-oldrel: msarc_1.4.5.zip |
OS X El Capitan binaries: | r-release: not available |
OS X Mavericks binaries: | r-oldrel: msarc_1.4.5.tgz |
Old sources: | msarc archive |
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