PROFANCY: The package can prioritize candidate disease metabolites based on global functional relationships between metabolites in the context of metabolic pathways

The package can prioritize the candidate disease metabolites based on the assumption that functionally related metabolites tend to associate with the same or similar diseases in the context of metabolic pathway. The PROFANCY package (1) prioritizes the disease metabolites from global functional similarity and local modularity of the metabolic network; (2) allows users to select default metabolites or input their interested metabolites as seed nodes or candidate nodes (3) can prioritize the candidate metabolites in KEGG or EHMN metabolic network.

Version: 1.0
Depends: R (≥ 2.15.2), Matrix, lattice, igraph
Published: 2013-07-12
Author: Qianlan Yao, Desi Shang, Chunquan Li
Maintainer: Qianlan Yao <yaoqianlan at>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
CRAN checks: PROFANCY results


Reference manual: PROFANCY.pdf
Vignettes: PROFANCY Overview
Package source: PROFANCY_1.0.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
OS X El Capitan binaries: r-release: PROFANCY_1.0.tgz
OS X Mavericks binaries: r-oldrel: PROFANCY_1.0.tgz


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