We implement multisite causal mediation analysis using the methods proposed by Qin and Hong (in press). It enables causal mediation analysis in multisite trials, in which individuals are assigned to a treatment or a control group at each site. It allows for estimation and hypothesis testing for not only the population average but also the between-site variance of direct and indirect effects. This strategy conveniently relaxes the assumption of no treatment-by-mediator interaction while greatly simplifying the outcome model specification without invoking strong distributional assumptions.
Version: | 0.0.1 |
Depends: | R (≥ 3.1.0), lme4, statmod, Matrix |
Published: | 2017-02-26 |
Author: | Xu Qin, Guanglei Hong |
Maintainer: | Xu Qin <xuqin at uchicago.edu> |
BugReports: | https://github.com/Xu-Qin/MultisiteMediation/issues |
License: | GPL-2 |
URL: | https://github.com/Xu-Qin/MultisiteMediation |
NeedsCompilation: | no |
CRAN checks: | MultisiteMediation results |
Reference manual: | MultisiteMediation.pdf |
Package source: | MultisiteMediation_0.0.1.tar.gz |
Windows binaries: | r-devel: MultisiteMediation_0.0.1.zip, r-release: MultisiteMediation_0.0.1.zip, r-oldrel: MultisiteMediation_0.0.1.zip |
OS X El Capitan binaries: | r-release: MultisiteMediation_0.0.1.tgz |
OS X Mavericks binaries: | r-oldrel: MultisiteMediation_0.0.1.tgz |
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