Phase I/II adaptive dose-finding design for combination studies. Several methods are proposed depending on the type of combinations: (1) the combination of two cytotoxic agents, and (2) combination of a molecularly targeted agent with a cytotoxic agent.
Version: | 2.3 |
Depends: | R (≥ 3.4.0) |
LinkingTo: | RcppArmadillo (≥ 0.7.100), BH (≥ 1.55), RcppProgress (≥ 0.2.1), Rcpp |
Published: | 2017-05-22 |
Author: | Marie-Karelle Riviere and Jacques-Henri Jourdan |
Maintainer: | Marie-Karelle Riviere <eldamjh at gmail.com> |
License: | GPL-3 |
Copyright: | src/arms.c and src/arms.h are copyright Wally Gilks. All other files are copyright Institut de Recherches Internationales Servier and Institut national de la sante et de la recherche medicale. |
NeedsCompilation: | yes |
In views: | ExperimentalDesign |
CRAN checks: | dfcomb results |
Reference manual: | dfcomb.pdf |
Package source: | dfcomb_2.3.tar.gz |
Windows binaries: | r-devel: dfcomb_2.3.zip, r-release: dfcomb_2.3.zip, r-oldrel: dfcomb_2.2.zip |
OS X El Capitan binaries: | r-release: dfcomb_2.3.tgz |
OS X Mavericks binaries: | r-oldrel: dfcomb_2.2.tgz |
Old sources: | dfcomb archive |
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