coxme: Mixed Effects Cox Models

Cox proportional hazards models containing Gaussian random effects, also known as frailty models.

Version: 2.2-10
Priority: optional
Depends: survival (≥ 2.36.14), methods, bdsmatrix (≥ 1.3)
Imports: nlme, Matrix (≥ 1.0)
LinkingTo: bdsmatrix
Suggests: mvtnorm, kinship2
Published: 2018-05-13
Author: Terry M. Therneau [aut, cre]
Maintainer: Terry M. Therneau <therneau at>
License: LGPL-2
Copyright: see file COPYRIGHTS
NeedsCompilation: yes
Materials: NEWS
In views: Survival
CRAN checks: coxme results


Reference manual: coxme.pdf
Vignettes: Mixed Effects Cox Models
Coxme and the Laplace Approximation
The lmekin function
Special Variance Structures
Package source: coxme_2.2-10.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
OS X binaries: r-release: coxme_2.2-10.tgz, r-oldrel: coxme_2.2-10.tgz
Old sources: coxme archive

Reverse dependencies:

Reverse depends: GWAF
Reverse imports: famSKATRC, KMgene, mlmm.gwas, RVFam, seqMeta, StatCharrms
Reverse suggests: AICcmodavg, car, gap, lsmeans, multcomp
Reverse enhances: emmeans, MuMIn


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