Assorted tools for genetic association analyses. The current focus is on implementing (either exactly or approximately) regression analyses using summary statistics instead of using subject-specific data. So far, functions exist to support multi-SNP risk score analyses, multi-SNP conditional regression analyses, and multi-phenotype analyses, using summary statistics. There are helper functions for reading and manipulating subject-specific genotype data, which provide a platform for calculating the summary statistics, or for using R to conduct other analyses not supported by specific GWAS analysis tools.
| Version: | 0.0.8 |
| Depends: | R (≥ 2.4.0), survival |
| Published: | 2013-01-11 |
| Author: | Toby Johnson |
| Maintainer: | Toby Johnson <Toby.x.Johnson at gsk.com> |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | no |
| Materials: | ChangeLog |
| CRAN checks: | gtx results |
| Reference manual: | gtx.pdf |
| Vignettes: |
Efficient Calculation for Multi-SNP Genetic Risk Scores |
| Package source: | gtx_0.0.8.tar.gz |
| Windows binaries: | r-devel: gtx_0.0.8.zip, r-release: gtx_0.0.8.zip, r-oldrel: gtx_0.0.8.zip |
| OS X binaries: | r-release: gtx_0.0.8.tgz, r-oldrel: gtx_0.0.8.tgz |
| Old sources: | gtx archive |
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