Assorted tools for genetic association analyses. The current focus is on implementing (either exactly or approximately) regression analyses using summary statistics instead of using subject-specific data. So far, functions exist to support multi-SNP risk score analyses, multi-SNP conditional regression analyses, and multi-phenotype analyses, using summary statistics. There are helper functions for reading and manipulating subject-specific genotype data, which provide a platform for calculating the summary statistics, or for using R to conduct other analyses not supported by specific GWAS analysis tools.
Version: | 0.0.8 |
Depends: | R (≥ 2.4.0), survival |
Published: | 2013-01-11 |
Author: | Toby Johnson |
Maintainer: | Toby Johnson <Toby.x.Johnson at gsk.com> |
License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
NeedsCompilation: | no |
Materials: | ChangeLog |
CRAN checks: | gtx results |
Reference manual: | gtx.pdf |
Vignettes: |
Efficient Calculation for Multi-SNP Genetic Risk Scores |
Package source: | gtx_0.0.8.tar.gz |
Windows binaries: | r-devel: gtx_0.0.8.zip, r-release: gtx_0.0.8.zip, r-oldrel: gtx_0.0.8.zip |
OS X binaries: | r-release: gtx_0.0.8.tgz, r-oldrel: gtx_0.0.8.tgz |
Old sources: | gtx archive |
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