Initial metabolic networks often inaccurately predict in-silico growth or non-growth if compared to in-vivo data. This package refines metabolic network models by making networks changes (i.e., removing, adding, changing reversibility of reactions; adding and removing biomass metabolites) and simultaneously matching sets of experimental growth and non-growth data (e.g., KO-mutants, mutants grown under different media conditions,...)
| Version: | 1.2 |
| Depends: | R (≥ 2.12.0), sybil (≥ 1.1.7), methods |
| Suggests: | cplexAPI (≥ 1.2.1) |
| Published: | 2016-08-12 |
| Author: | Daniel Hartleb |
| Maintainer: | Daniel Hartleb <daniel.hartleb at hhu.de> |
| License: | GPL-3 |
| NeedsCompilation: | no |
| CRAN checks: | GlobalFit results |
| Reference manual: | GlobalFit.pdf |
| Package source: | GlobalFit_1.2.tar.gz |
| Windows binaries: | r-devel: GlobalFit_1.2.zip, r-release: GlobalFit_1.2.zip, r-oldrel: GlobalFit_1.2.zip |
| OS X binaries: | r-release: GlobalFit_1.2.tgz, r-oldrel: GlobalFit_1.2.tgz |
| Old sources: | GlobalFit archive |
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