Facilities for running simulations from ordinary differential equation (ODE) models, such as pharmacometrics and other compartmental models. A compilation manager translates the ODE model into C, compiles it, and dynamically loads the object code into R for improved computational efficiency. An event table object facilitates the specification of complex dosing regimens (optional) and sampling schedules. NB: The use of this package requires both C and Fortran compilers, for details on their use with R please see Section 6.3, Appendix A, and Appendix D in the "R Administration and Installation" manual. Also the code is mostly released under GPL. The VODE and LSODA are in the public domain. The information is available in the inst/COPYRIGHTS.
| Version: | 0.8.0-9 |
| Depends: | R (≥ 3.3.0) |
| Imports: | utils, methods, digest, rex, dparser (≥ 0.1.8), brew, memoise, magrittr, Rcpp (≥ 0.12.3), inline, Matrix, R.utils, PreciseSums (≥ 0.3), n1qn1 (≥ 6.0.1-2), mvnfast, cli, crayon |
| LinkingTo: | dparser (≥ 0.1.8), Rcpp (≥ 0.12.3), RcppArmadillo (≥ 0.5.600.2.0), PreciseSums (≥ 0.3) |
| Suggests: | knitr, nlme, shiny, tcltk, testthat, devtools, covr, rmarkdown, SnakeCharmR, rSymPy, dplyr, tidyr, tibble, curl, ggplot2, gridExtra, microbenchmark, scales, stringi, htmltools, reticulate |
| Published: | 2018-12-10 |
| Author: | Matthew L. Fidler [aut], Melissa Hallow [aut], Wenping Wang [aut, cre], Zufar Mulyukov [ctb], Justin Wilkins [ctb], Simon Frost [ctb], Heng Li [ctb], Yu Feng [ctb], Alan Hindmarsh [ctb], Linda Petzold [ctb], Ernst Hairer [ctb], Gerhard Wanner [ctb], Johannes Pfeifer [ctb], Robert B. Schnabel [ctb], Elizabeth Eskow [ctb], J Colinge [ctb], Hadley Wickham [ctb], G Grothendieck [ctb], Robert Gentleman [ctb], Ross Ihaka [ctb], R core team [cph], odepack authors [cph] |
| Maintainer: | Wenping Wang <wwang8198 at gmail.com> |
| BugReports: | https://github.com/nlmixrdevelopment/RxODE/issues |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| Copyright: | see file COPYRIGHTS |
| URL: | https://www.r-project.org, https://github.com/nlmixrdevelopment/RxODE |
| NeedsCompilation: | yes |
| Citation: | RxODE citation info |
| In views: | HighPerformanceComputing |
| CRAN checks: | RxODE results |
| Reference manual: | RxODE.pdf |
| Vignettes: |
RxODE Covariates RxODE data frames RxODE Event Coding Introduction to RxODE RxODE Solved Systems and ODEs RxODE and Shiny RxODE Simulation RxODE Jacobian specification and Stiff Systems RxODE ODE solving syntax RxODE Transit Compartment Models |
| Package source: | RxODE_0.8.0-9.tar.gz |
| Windows binaries: | r-devel: RxODE_0.8.0-9.zip, r-release: RxODE_0.8.0-9.zip, r-oldrel: RxODE_0.8.0-9.zip |
| OS X binaries: | r-release: RxODE_0.8.0-9.tgz, r-oldrel: RxODE_0.8.0-9.tgz |
| Old sources: | RxODE archive |
| Reverse imports: | nlmixr |
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