A normalization method for single-cell UMI count data using a variance stabilizing transformation. The transformation is based on a negative binomial regression model with regularized parameters. As part of the same regression framework, this package also provides functions for batch correction, and data correction. See Hafemeister and Satija 2019 <doi:10.1101/576827> for more details.
Version: | 0.2.0 |
Depends: | R (≥ 3.0.2) |
Imports: | MASS, Matrix, methods, future, future.apply, ggplot2, reshape2, gridExtra, Rcpp |
LinkingTo: | Rcpp (≥ 0.11.0), RcppEigen |
Suggests: | irlba, testthat |
Published: | 2019-04-12 |
Author: | Christoph Hafemeister |
Maintainer: | Christoph Hafemeister <chafemeister at nygenome.org> |
BugReports: | https://github.com/ChristophH/sctransform/issues |
License: | GPL-3 | file LICENSE |
URL: | https://github.com/ChristophH/sctransform |
NeedsCompilation: | yes |
Materials: | README |
CRAN checks: | sctransform results |
Reference manual: | sctransform.pdf |
Package source: | sctransform_0.2.0.tar.gz |
Windows binaries: | r-devel: sctransform_0.1.0.zip, r-release: sctransform_0.1.0.zip, r-oldrel: sctransform_0.1.0.zip |
OS X binaries: | r-release: sctransform_0.1.0.tgz, r-oldrel: sctransform_0.1.0.tgz |
Old sources: | sctransform archive |
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