Compute standard Non-Compartmental Analysis (NCA) parameters and summarize them. In addition to this core work, it also provides standardized plotting routines, basic assessments for biocomparison or drug interaction, and model-based estimation routines for calculating doses to reach specific values of AUC or Cmax.
| Version: | 0.8.5 |
| Imports: | dplyr (≥ 0.5.0), digest, plyr, nlme, parallel, lattice, rlang, stats, tidyr, utils |
| Suggests: | cowplot, ggplot2, knitr, rmarkdown, testthat |
| Published: | 2018-06-13 |
| Author: | Bill Denney [aut, cre], Clare Buckeridge [aut], Sridhar Duvvuri [ctb] |
| Maintainer: | Bill Denney <wdenney at humanpredictions.com> |
| BugReports: | https://github.com/billdenney/pknca/issues |
| License: | AGPL-3 |
| URL: | https://github.com/billdenney/pknca |
| NeedsCompilation: | no |
| Citation: | PKNCA citation info |
| Materials: | README NEWS |
| CRAN checks: | PKNCA results |
| Reference manual: | PKNCA.pdf |
| Vignettes: |
AUC Calculation with PKNCA Data Cleaning in PKNCA Introduction to PKNCA and Usage Instructions Methods Used for Dose-Aware Concentration Interpolation/Extrapolation Options for Controlling PKNCA PKNCA Validation Selection of Calculation Intervals Superposition of Pharmacokinetic Data Writing PKNCA Parameter Functions |
| Package source: | PKNCA_0.8.5.tar.gz |
| Windows binaries: | r-devel: PKNCA_0.8.5.zip, r-release: PKNCA_0.8.5.zip, r-oldrel: PKNCA_0.8.5.zip |
| OS X binaries: | r-release: PKNCA_0.8.5.tgz, r-oldrel: PKNCA_0.8.5.tgz |
| Old sources: | PKNCA archive |
| Reverse imports: | pmxTools |
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