GWsignif: Estimating Genome-Wide Significance for Whole Genome Sequencing Studies, Either Single SNP Tests or Region-Based Tests

The correlations and linkage disequilibrium between tests can vary as a function of minor allele frequency thresholds used to filter variants, and also varies with different choices of test statistic for region-based tests. Appropriate genome-wide significance thresholds can be estimated empirically through permutation on only a small proportion of the whole genome.

Version: 1.2
Published: 2016-09-12
Author: ChangJiang Xu and Celia M.T. Greenwood
Maintainer: ChangJiang Xu <changjiang.h.xu at>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
CRAN checks: GWsignif results


Reference manual: GWsignif.pdf
Package source: GWsignif_1.2.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
OS X binaries: r-release: GWsignif_1.2.tgz, r-oldrel: GWsignif_1.2.tgz
Old sources: GWsignif archive


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