Applying the global sensitivity analysis workflow to investigate the parameter uncertainty and sensitivity in pharmacokinetic (PK) models, especially the physiologically-based pharmacokinetic (PBPK) model with multivariate outputs. The package also provide some functions to check the sensitivity measures and its convergence of model parameters.
Version: | 1.1.2 |
Depends: | R (≥ 3.5) |
Imports: | ggplot2, data.table, deSolve, dplyr, getPass, magrittr, reshape |
Suggests: | knitr, rmarkdown, testthat, viridis |
Published: | 2019-06-30 |
Author: | Nan-Hung Hsieh |
Maintainer: | Nan-Hung Hsieh <nhsieh at cvm.tamu.edu> |
BugReports: | https://github.com/nanhung/pksensi/issues |
License: | GPL-3 | file LICENSE |
URL: | https://github.com/nanhung/pksensi, https://nanhung.rbind.io/pksensi |
NeedsCompilation: | no |
Materials: | NEWS |
CRAN checks: | pksensi results |
Reference manual: | pksensi.pdf |
Vignettes: |
Acetaminophen-PBPK model One-compartment PK model |
Package source: | pksensi_1.1.2.tar.gz |
Windows binaries: | r-devel: pksensi_1.1.2.zip, r-release: pksensi_1.1.2.zip, r-oldrel: pksensi_1.1.2.zip |
OS X binaries: | r-release: pksensi_1.1.2.tgz, r-oldrel: pksensi_1.1.2.tgz |
Old sources: | pksensi archive |
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