RxODE: Facilities for Simulating from ODE-Based Models

Facilities for running simulations from ordinary differential equation (ODE) models, such as pharmacometrics and other compartmental models. A compilation manager translates the ODE model into C, compiles it, and dynamically loads the object code into R for improved computational efficiency. An event table object facilitates the specification of complex dosing regimens (optional) and sampling schedules. NB: The use of this package requires both C and Fortran compilers, for details on their use with R please see Section 6.3, Appendix A, and Appendix D in the "R Administration and Installation" manual. Also the code is mostly released under GPL. The VODE and LSODA are in the public domain. The information is available in the inst/COPYRIGHTS.

Version: 0.9.1-7
Depends: R (≥ 3.5.0)
Imports: Matrix, PreciseSums (≥ 0.3), Rcpp (≥ 0.12.3), brew, cli, crayon, digest, dparser (≥ 0.1.8), ggforce, ggplot2, inline, magrittr, memoise, methods, mvnfast, pillar, rex, sys, units (≥ 0.6-0), utils, assertthat, lotri, remotes
LinkingTo: dparser (≥ 0.1.8), Rcpp (≥ 0.12.3), RcppArmadillo (≥ 0.9.300.2.0), PreciseSums (≥ 0.3)
Suggests: knitr, DT, data.table, nlme, shiny, tcltk, testthat, usethis, devtools, covr, rmarkdown, SnakeCharmR, dplyr (≥ 0.8.0), tidyr, tibble, curl, gridExtra, microbenchmark, scales, stringi, htmltools, reticulate, rlang, installr
Published: 2019-10-27
Author: Matthew L. Fidler ORCID iD [aut], Melissa Hallow [aut], Wenping Wang [aut, cre], Zufar Mulyukov [ctb], Justin Wilkins ORCID iD [ctb], Simon Frost [ctb], Goro Fuji [ctb], Morwenn [ctb], Heng Li [ctb], Yu Feng [ctb], Alan Hindmarsh [ctb], Linda Petzold [ctb], Ernst Hairer [ctb], Gerhard Wanner [ctb], J Colinge [ctb], Hadley Wickham [ctb], G Grothendieck [ctb], Robert Gentleman [ctb], Daniel C. Dillon [ctb], Ross Ihaka [ctb], R core team [cph], odepack authors [cph]
Maintainer: Wenping Wang <wwang8198 at gmail.com>
BugReports: https://github.com/nlmixrdevelopment/RxODE/issues
License: GPL (≥ 3)
Copyright: see file COPYRIGHTS
URL: https://nlmixrdevelopment.github.io/RxODE/
NeedsCompilation: yes
Language: en-US
Citation: RxODE citation info
CRAN checks: RxODE results


Reference manual: RxODE.pdf
Vignettes: Introduction to RxODE
RxODE ODE solving syntax
Package source: RxODE_0.9.1-7.tar.gz
Windows binaries: r-devel: RxODE_0.9.1-7.zip, r-release: RxODE_0.9.1-7.zip, r-oldrel: RxODE_0.9.1-7.zip
OS X binaries: r-release: RxODE_0.9.1-4.tgz, r-oldrel: RxODE_0.9.1-4.tgz
Old sources: RxODE archive

Reverse dependencies:

Reverse imports: nlmixr
Reverse linking to: nlmixr
Reverse suggests: xgxr


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