SITH: A Spatial Model of Intra-Tumor Heterogeneity

Implements a three-dimensional stochastic model of cancer growth and mutation similar to the one described in Waclaw et al. (2015) <doi:10.1038/nature14971>. Allows for interactive 3D visualizations of the simulated tumor. Provides a comprehensive summary of the spatial distribution of mutants within the tumor. Contains functions which create synthetic sequencing datasets from the generated tumor.

Version: 1.0.0
Depends: R (≥ 4.0.0)
Imports: Rcpp (≥ 1.0.4), scatterplot3d, stats, graphics, grDevices
LinkingTo: Rcpp
Suggests: rgl, knitr, rmarkdown, testthat
Published: 2020-07-01
Author: Phillip B. Nicol
Maintainer: Phillip B. Nicol <philnicol740 at gmail.com>
BugReports: https://github.com/phillipnicol/SITH/issues
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
URL: https://github.com/phillipnicol/SITH
NeedsCompilation: yes
Materials: NEWS
CRAN checks: SITH results

Downloads:

Reference manual: SITH.pdf
Vignettes: SITH-introduction
Package source: SITH_1.0.0.tar.gz
Windows binaries: r-devel: not available, r-release: not available, r-oldrel: not available
macOS binaries: r-release: not available, r-oldrel: not available

Linking:

Please use the canonical form https://CRAN.R-project.org/package=SITH to link to this page.