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Meta-Analysis of Region-Based Tests of Rare DNA Variants

Computes necessary information to meta analyze region-based tests for rare genetic variants (e.g. SKAT, T1) in individual studies, and performs meta analysis.

You can install:

If you encounter a clear bug, please file a minimal reproducible example on github.

seqMeta 1.6.7

seqMeta 1.6.6

seqMeta 1.6.5

seqMeta 1.6.0


prepScores2 is a drop in replacement for prepScores, prepScoresX and prepCox. The only difference is the family argument should be text. gaussian() becomes "gaussian", binomial() becomes "binomial" and "cox" is used for survival models. prepScores2 is much faster in cases where genotype imputation occurs.