st: Shrinkage t Statistic and Correlation-Adjusted t-Score

Implements the "shrinkage t" statistic introduced in Opgen-Rhein and Strimmer (2007) <doi:10.2202/1544-6115.1252> and a shrinkage estimate of the "correlation-adjusted t-score" (CAT score) described in Zuber and Strimmer (2009) <doi:10.1093/bioinformatics/btp460>. It also offers a convenient interface to a number of other regularized t-statistics commonly employed in high-dimensional case-control studies.

Version: 1.2.6
Depends: R (≥ 3.0.2), sda (≥ 1.3.7), fdrtool (≥ 1.2.15), corpcor (≥ 1.6.9)
Imports: graphics, stats
Suggests: limma, samr
Published: 2020-09-24
Author: Rainer Opgen-Rhein, Verena Zuber, and Korbinian Strimmer.
Maintainer: Korbinian Strimmer <strimmerlab at>
License: GPL (≥ 3)
NeedsCompilation: no
Materials: NEWS
CRAN checks: st results


Reference manual: st.pdf
Package source: st_1.2.6.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release: st_1.2.6.tgz, r-oldrel: st_1.2.6.tgz
Old sources: st archive

Reverse dependencies:

Reverse depends: BioMark, MAclinical
Reverse suggests: CMA, GiANT


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