Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.
| Version: |
3.0.3 |
| Depends: |
R (≥ 3.4.0) |
| Imports: |
methods, stats, utils, graphics, tools, Rcpp (≥ 1.0.0) |
| LinkingTo: |
Rcpp |
| Suggests: |
parallel, ggplot2 (≥ 2.2.0), testthat (≥ 2.0.0), mnormt (≥
1.5-7), knitr (≥ 1.19), rmarkdown (≥ 1.10) |
| Published: |
2020-12-01 |
| Author: |
Gernot Wassmer [aut],
Friedrich Pahlke [aut, cre] |
| Maintainer: |
Friedrich Pahlke <friedrich.pahlke at rpact.com> |
| BugReports: |
https://www.rpact.org/bugreport |
| License: |
LGPL-3 |
| URL: |
https://www.rpact.org |
| NeedsCompilation: |
yes |
| Language: |
en-US |
| Materials: |
README NEWS |
| CRAN checks: |
rpact results |