It has been designed to calculate the required sample size in randomized clinical trials with composite endpoints. This package also includes functions to calculate the probability of observing the composite endpoint and the expected effect on the composite endpoint, among others. The methods implemented can be found in Bofill & Gómez (2019) <doi:10.1002/sim.8092> and Gómez & Lagakos (2013) <doi:10.1002/sim.5547>.
Version: | 1.7 |
Imports: | stats, copula, ggplot2, rootSolve, numDeriv |
Published: | 2021-02-02 |
Author: | Marta Bofill Roig [aut, cre], Jordi Cortes Martinez [aut], Guadalupe Gomez Melis [ctb] |
Maintainer: | Marta Bofill Roig <marta.bofill.roig at upc.edu> |
License: | GPL-3 |
NeedsCompilation: | no |
CRAN checks: | CompAREdesign results |
Reference manual: | CompAREdesign.pdf |
Package source: | CompAREdesign_1.7.tar.gz |
Windows binaries: | r-devel: CompAREdesign_1.7.zip, r-release: CompAREdesign_1.7.zip, r-oldrel: CompAREdesign_1.7.zip |
macOS binaries: | r-release: CompAREdesign_1.7.tgz, r-oldrel: CompAREdesign_1.7.tgz |
Old sources: | CompAREdesign archive |
Please use the canonical form https://CRAN.R-project.org/package=CompAREdesign to link to this page.