CompAREdesign: Statistical Functions for the Design of Studies with Composite Endpoints

It has been designed to calculate the required sample size in randomized clinical trials with composite endpoints. This package also includes functions to calculate the probability of observing the composite endpoint and the expected effect on the composite endpoint, among others. The methods implemented can be found in Bofill & Gómez (2019) <doi:10.1002/sim.8092> and Gómez & Lagakos (2013) <doi:10.1002/sim.5547>.

Version: 1.7
Imports: stats, copula, ggplot2, rootSolve, numDeriv
Published: 2021-02-02
Author: Marta Bofill Roig [aut, cre], Jordi Cortes Martinez [aut], Guadalupe Gomez Melis [ctb]
Maintainer: Marta Bofill Roig <marta.bofill.roig at>
License: GPL-3
NeedsCompilation: no
CRAN checks: CompAREdesign results


Reference manual: CompAREdesign.pdf
Package source: CompAREdesign_1.7.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release: CompAREdesign_1.7.tgz, r-oldrel: CompAREdesign_1.7.tgz
Old sources: CompAREdesign archive


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