RxODE: Facilities for Simulating from ODE-Based Models

Facilities for running simulations from ordinary differential equation ('ODE') models, such as pharmacometrics and other compartmental models. A compilation manager translates the ODE model into C, compiles it, and dynamically loads the object code into R for improved computational efficiency. An event table object facilitates the specification of complex dosing regimens (optional) and sampling schedules. NB: The use of this package requires both C and Fortran compilers, for details on their use with R please see Section 6.3, Appendix A, and Appendix D in the "R Administration and Installation" manual. Also the code is mostly released under GPL. The 'VODE' and 'LSODA' are in the public domain. The information is available in the inst/COPYRIGHTS.

Version: 1.0.4
Depends: R (≥ 3.6.0)
Imports: PreciseSums (≥ 0.3), Rcpp (≥ 0.12.3), assertthat, backports, checkmate, cli (≥ 2.0.0), dparser (≥ 0.1.8), ggplot2, inline, lotri (≥ 0.2.2), magrittr, memoise, methods, rex, qs, sys, units (≥ 0.6-0), tools, utils
LinkingTo: dparser (≥ 0.1.8), PreciseSums (≥ 0.3), RcppEigen (≥, RcppArmadillo (≥ 0.9.300.2.0), sitmo, StanHeaders (≥ 2.18.0), BH, checkmate, qs
Suggests: spelling, Matrix, DT, covr, crayon, curl, data.table (≥ 1.12.4), devtools, digest, dplyr (≥ 0.8.0), ggrepel, gridExtra, htmltools, knitr, learnr, microbenchmark, nlme, remotes, rlang, rmarkdown, scales, shiny, stringi, symengine, testthat, tidyr, usethis, vdiffr, xgxr, pillar, tibble, rsconnect, patchwork
Published: 2021-02-24
Author: Matthew L. Fidler ORCID iD [aut], Melissa Hallow [aut], Wenping Wang [aut, cre], Zufar Mulyukov [ctb], Alan Hindmarsh [ctb], Awad H. Al-Mohy [ctb], Matt Dowle [ctb], Cleve Moler [ctb], David Cooley [ctb], Daniel C. Dillon [ctb], Drew Schmidt [ctb], Arun Srinivasan [ctb], Ernst Hairer [ctb], Gerhard Wanner [ctb], Goro Fuji [ctb], Hadley Wickham [ctb], Jack Dongarra [ctb], Linda Petzold [ctb], Martin Maechler [ctb], Matteo Fasiolo [ctb], Morwenn [ctb], Nicholas J. Higham [ctb], Roger B. Sidje [ctb], Simon Frost [ctb], Kevin Ushey [ctb], Yu Feng [ctb]
Maintainer: Wenping Wang <wwang8198 at gmail.com>
BugReports: https://github.com/nlmixrdevelopment/RxODE/issues
License: GPL (≥ 3)
Copyright: see file COPYRIGHTS
URL: https://nlmixrdevelopment.github.io/RxODE/
NeedsCompilation: yes
Language: en-US
Citation: RxODE citation info
CRAN checks: RxODE results


Reference manual: RxODE.pdf
Vignettes: Introduction to RxODE
RxODE ODE solving syntax
Package source: RxODE_1.0.4.tar.gz
Windows binaries: r-devel: RxODE_1.0.4.zip, r-release: RxODE_1.0.4.zip, r-oldrel: not available
macOS binaries: r-release: RxODE_1.0.4.tgz, r-oldrel: not available
Old sources: RxODE archive


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