Provides routines to compute normalised prediction distribution errors, a metric designed to evaluate non-linear mixed effect models such as those used in pharmacokinetics and pharmacodynamics. Documentation about 'npde' is provided by a comprehensive user guide on the github repository (<https://github.com/ecomets/npde30/blob/main/userguide_npde_3.0.pdf>), and references concerning the methods include the papers by Brendel et al. (2006, <doi:10.1007/s11095-006-9067-5>; 2010, <doi:10.1007/s10928-009-9143-7>), Comets et al. (2008, <doi:10.1016/j.cmpb.2007.12.002> ; 2010, <http://journal-sfds.fr/article/view/45>), and Nguyen et al. (2012, <doi:10.1007/s10928-012-9264-2>). See 'citation("npde")' for details.
Version: | 3.0 |
Depends: | gridExtra, ggplot2, grid |
Imports: | methods, scales, mclust, testthat, rlang |
Published: | 2021-02-25 |
Author: | Emmanuelle Comets |
Maintainer: | Emmanuelle Comets <emmanuelle.comets at inserm.fr> |
License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
URL: | https://github.com/ecomets/npde30/blob/main/userguide_npde_3.0.pdf |
NeedsCompilation: | no |
CRAN checks: | npde results |
Reference manual: | npde.pdf |
Package source: | npde_3.0.tar.gz |
Windows binaries: | r-devel: npde_3.0.zip, r-release: npde_3.0.zip, r-oldrel: npde_3.0.zip |
macOS binaries: | r-release: npde_3.0.tgz, r-oldrel: not available |
Old sources: | npde archive |
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