VNM: Finding Multiple-Objective Optimal Designs for the 4-Parameter Logistic Model

Provide tools for finding multiple-objective optimal designs for estimating the shape of dose-response, the ED50 (the dose producing an effect midway between the expected responses at the extreme doses) and the MED (the minimum effective dose level) for the 2,3,4-parameter logistic models and for evaluating its efficiencies for the three objectives. The acronym VNM stands for V-algorithm using Newton Raphson method to search multiple-objective optimal design.

Version: 7.1
Depends: methods
Imports: graphics, Rcpp
LinkingTo: Rcpp
Published: 2018-05-17
Author: Seung Won Hyun, Weng Kee Wong, and Yarong Yang
Maintainer: Yarong Yang <yarongyang78 at>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: yes
Citation: VNM citation info
In views: ExperimentalDesign
CRAN checks: VNM results


Reference manual: VNM.pdf
Package source: VNM_7.1.tar.gz
Windows binaries: r-devel:, r-devel-UCRT:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): VNM_7.1.tgz, r-release (x86_64): VNM_7.1.tgz, r-oldrel: VNM_7.1.tgz
Old sources: VNM archive


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