ubiquity: PKPD, PBPK, and Systems Pharmacology Modeling Tools
Complete work flow for the analysis of pharmacokinetic pharmacodynamic (PKPD), physiologically-based pharmacokinetic (PBPK) and systems pharmacology models including: creation of ordinary differential equation-based models, pooled parameter estimation, individual/population based simulations, rule-based simulations for clinical trial design and modeling assays, deployment with a customizable 'Shiny' app, and non-compartmental analysis. System-specific analysis templates can be generated and each element includes integrated reporting with 'PowerPoint' and 'Word'.
| Version: | 1.0.5 |
| Depends: | R (≥ 3.5.0) |
| Imports: | deSolve, dplyr (≥ 1.0.0), digest, doParallel, flextable, foreach, gridExtra, grid, ggplot2, knitr, magrittr, MASS, officer (≥ 0.3.7), optimx, PKNCA, pso, readxl, rmarkdown, rhandsontable, rstudioapi, scales, stats, stringr, shiny |
| Suggests: | GA, GGally, gridGraphics, webshot, testthat, ggrepel |
| Published: | 2021-04-25 |
| Author: | John Harrold 
[aut, cre] |
| Maintainer: | John Harrold <john.m.harrold at gmail.com> |
| BugReports: | https://github.com/john-harrold/ubiquity/issues |
| License: | BSD_2_clause + file LICENSE |
| URL: | https://ubiquity.tools/rworkflow |
| NeedsCompilation: | no |
| SystemRequirements: | Perl |
| Materials: | README |
| CRAN checks: | ubiquity results |
Downloads:
| Reference manual: | ubiquity.pdf |
| Vignettes: |
Deployment Estimation Language Noncompartmental Analysis Report Generation Simulation Titration/Rule-Based Simulations |
| Package source: | ubiquity_1.0.5.tar.gz |
| Windows binaries: | r-devel: ubiquity_1.0.5.zip, r-release: ubiquity_1.0.5.zip, r-oldrel: ubiquity_1.0.5.zip |
| macOS binaries: | r-release (arm64): ubiquity_1.0.5.tgz, r-release (x86_64): ubiquity_1.0.5.tgz, r-oldrel: ubiquity_1.0.5.tgz |
| Old sources: | ubiquity archive |
Linking:
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